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Across 3. protein coat surrounding the nucleic acid core of a virion 5. response in which antibodies are produced 7. vaccine capable of herd immunity 10. replication involving death and lysis of the host cell 14. microorganism that causes disease when the immune system is suppressed, when microbial antagonism is reduced, or when introduced into an abnormal area of the body 15. immunity in which the vertebrate has the ability to recognize and defend against distinct species or strains of invaders

Down 1. transfer of antibodies from another individual/source 2. acquired response to antigens in daily life or by disease/infection 4. faster and more effective response to re-exposure of antigens 6. type of endocytosis in which pathogens are moved/ingested into the cell and killed 8. proteins that bind to and "tag" antigens for destruction 9. attenuated, inactivated (killed), toxoid 11. blood, bone marrow, lungs, CSF, urine 12. infection involving the persistence of viral genome in the host cell, reactivated much later 13. immunity stimulated by a vaccination