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Across 1. increased urinary output 2. inhibits the secretion of insulin and glucagon from the pancreas 11. secrete insulin 12. secrete somatostatin 17. leading cause of blindness in adults 19. a life threatening complication of type 1 diabetes

Down 3. secrete glucagon 4. endocrine portion of the pancreas contains specialized cells 5. increases blood glucose by converting glycogen to glucose in the liver 6. major cause of death in people with diabetes 7. increased appetite 8. stimulates uptake of glucose by muscle and connective tissue 9. blood sugar level above the normal range 10. onset of high blood glucose levels during pregnancy 13. augments insulin secretion used for type 2 diabetes 14. increased thirst 15. blood sugar level below the normal range 16. clinical manifestation of diabetes 18. increases peripheral utilization of gulcose for type 2 patients with some endogenous insulin