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Across 1. the __ immune response involves lymphocytes, and form memories 4. a gland that produces oxytocin, growth hormone, and ACTH 5. this __ lobe is also called the NEUROHYPOPHYSIS 8. the __ route is how hormones produced by the cell regulate the activity of the cell that produced the hormone 9. the __ route is how hormones pass through the gap junctions (between) cells and alter functions of adjacent cells 14. antibody for antiviral, antitoxin, and antibacterial 15. the __ route is how a hormone is secreted into the space in between cells and the interstitial fluid carries them to the target organ (hormones often effect neighboring cells) 16. first line of defense against foreign particles; the physical barrier. 19. the __ route is how a hormone is transported via the blood to the target organ 20. this __ lobe is also called the ADENOHYPOPHYSIS 22. __-__ is the increase in hormone receptors on target cell 23. the __ route is how hormones diffuse through synaptic clefts similar to neurotransmitters 24. __ __ are responsible for cellular immune response 25. __ decreases blood calcium levels 26. an endocrine organ that releases a lot of "releasing hormones" like gonadotropin releasing hormone, corticotropin releasing hormone, and thyroid releasing hormone. 32. response of tissue to injury 35. pancreas releases this to slow mobilization and production of nutrients 37. antibody for early immune responses, blood cell antigens 38. when antibodies (or ability to make antibodies) are available for a particular antigen 39. __ is when the thyroid swells to produce more hormone (a goiter may present) 41. these hormone producing glands are on top of the kidneys 42. parathyroid hormone __ blood calcium levels 43. t cells differentiate into t cytotoxic cells, OR t __ cells. 44. non-classical hormones that act in a paracrine fashion; they are chemical derivatives of fatty acids 46. the pineal gland produces __ 47. T4 50. __ hormones have receptors located in the cytosol or nucleus of target cell 52. __ __ are responsible for humoral immune response 53. chemical messengers of inflammation that are released as a second line of defense (nonspecific) 54. a gland that usually exists in 2 pairs on each side of another gland; works on body's Ca and P levels 55. complex of protein structures designed to bind a hormone to elicit its cellular effects (found in cell membrane or nucleus) 61. amine hormones are biochemical modifications of the amino acid __ 62. the anterior lobe of the pituitary produces ACTH. what do these letters stand for? 64. from adrenals, regulates sodium and potassium levels in the blood 66. antibody needed for maturation of B cells 67. antibody that's part of allergic reactions 68. lutenizing hormone, follicle stimulating hormone, and __ are produced by the posterior pituitary and are involved in the regulation of reproductive processes 69. chemical substance that is produced by a ductless gland, released into the blood stream, and carried to other parts of the body where they produce a specific regulatory effect 70. parathyroid hormone promotes the formation of __ _ in kidney, which promotes the absorption of Calcium from the digestive tract 71. leukocyte __ is the signaling of leukocytes to come to a specific area that has been injured (complement proteins do this)

Down 2. an example of a steroid hormone 3. __ receptors in the uterus are increased before giving birth (estrogen stimulates this increase) 4. the parathyroid hormone increases excretion of __ in urine 6. __ is an example of an NSAID that works to inhibit prostaglandin effects of inflammation 7. molecules that stimulate an immune response 10. thyroid gland secretes thyroid hormone and __ 11. protein hormone; receptors for these are located in cell membranes 12. ADH (anti-diuretic) is produced by the posterior pituitary, and is involved in __ function 13. the __ gland regulates day/night cycles, as well as seasonal breeding cycles etc. 17. b and t cells are produced in the __ __ 18. these hormone-like fatty acid derivatives are a subclass of the eicosanoids, and are inhibited by NSAIDs 21. decreases blood glucose by stimulating glucose uptake into tissues 27. __ releasing hormone from the hypothalamus, stimulates the release of TSH from the anterior pituitary 28. this method of immunity trains the animal to produce antibodies before exposure to the "real" antigen 29. __ is the condition where the thyroid is underactive. symptoms involve cold and lethargy 30. a gland that produces hormones containing iodine 31. __ immunity is achieved temporarily, by the transfer of immunoglobulins or T cells 32. antibody that protects mucous membranes and surfaces 33. __ immunity is achieved by the response of one's own immune system 34. hormone from pancreas increases blood glucose 36. T3 38. protection against foreign entities 40. hyperparathyroidism can lead to __ in young animals. 42. an example of a peptide hormone 45. humoral immune response is related to __ 48. two things determine the magnitude of the effect a hormone has: one is amount of hormones present, and the other is the amount of __ present to receive the hormones 49. epinephrine and norepinephrine are __ produced by the adrenals 51. diets low in calcium will stimulate the release of ___ hormone. 53. t killer cells are release __ material into foreign cells to kill them 56. cholesterol precursor, 4 ring structure 57. the center of the adrenal gland 58. the part of the adrenal gland that produces glucocorticoids 59. parathyroid hormone will __ blood Phosphorus 60. __ is a fairly new addition to the endocrine system; it has hormones involved in weight maintenance and satiety 63. the __ route is how a hormone is secreted to the exterior of teh body where it interacts with a target organ (ex: hormones secreted into the lumen of digestive tract) 65. T cells differentiate in the __