| Down |
| 1. | the empire and people Pizzaro conquered in Peru |
| 2. | a forgotten building material recipe |
| 3. | largest island in the Caribbean |
| 6. | capital city of Italy |
| 8. | where Columbus thought he landed in 1492 |
| 9. | Lorenzo Medici's nickname |
| 10. | he pained The Birth of Venus |
| 11. | slaves were needed to grow this crop in the Caribbean |
| 12. | one of the 3 G's for going exploring |
| 13. | Portuguese sailor who found bottom of Africa |
| 15. | Lorenzo established the first one in Florence |
| 19. | type of government in Florence |
| 20. | the secret weapon Europeans had to kill off native Americans |
| 21. | navigation tool that shows where north is |
| 23. | mountain range in Switzerland |
| 24. | King Henry of Portugal's nickname |
| 27. | secular |
| 29. | what Savonarola thought renaissance art was |
| 32. | a device used to measure the location of stars |
| 34. | first European to sail under Africa to India and return |
| 35. | leader of the Catholic church |
| 36. | Spanish territory in the new world |
| 37. | island city and rival trade centre to Florence |
| 39. | Michelangelo's preferred art form |
| 40. | he was the first French sea captain to claim land in America |
| 41. | first European to get to China in 1200's |
| 43. | a fragile product Europeans wanted from China |
| 45. | why Florence, Venice and other city states got rich |
| 46. | he claimed Newfoundland for England |
| 49. | what renaissance Europe knew the world was not |
| 50. | short form for Holy Roman Empire |