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Across 1. pneumothorax, or collapsed _____, can be a serious complication of Marfan syndrome 5. the basic physical and functional unit of heredity 7. _____ excavatum or carinatum, deformities of the breastbone, also called funnel chest or pigeon breast 8. Marfan syndrome is caused by a mutation in the fibrillin gene on _____ 15 in the human genome 10. bone and joint doctor 12. a tear in the inner lining of the aorta (2 Words) 14. spider fingers 17. heart doctor 18. the large blood vessel that carries blood away from the heart 20. part of the heart that regulated blood flow by opening and closing with each heartbeat (2 Words) 21. dislocated _____ of the eye is a common feature in Marfan syndrome and can cause severe vision problems 22. Jonathan Larson, creator of the hit musical _____ died of Marfan related causes before his show even opened 23. a curving of the _____ is called scoliosis

Down 1. U.S. president thought by some to have had marfan syndrome 2. in biology, the study of inheritance 3. an abnormal ballooning of a blood vessel 4. bones and joints 6. a painless test that uses sound waves to take pictures of the heart and blood vessels 9. eye doctor 11. tissue that provides support and structure throughout the body (2 Words) 13. flat feet, also called _____ _____, that may be larger than normal make it difficult to find shoes that fit (2 Words) 15. extremities (3 Words) 16. a protein that is essential for the formation of elastic fibers found in connective tissue 19. Antoine _____ is the French pediatrician who first identified the disorder