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Across 1. required for egg production and formation of characteristics associated with being a female 5. gland that controls the body's metabolism with the hormone thyroxine 8. gland that produces insulin and glucagon 10. hormone produced in the male gonads 12. part of the brain that directs and controls the pituitary gland 13. hormone produced in the female gonads 16. hormone commonly referred to as adrenaline 19. gland that releases its products directly into the bloodstream 20. glands that release hormones to help the body deal with "fight or flight" 21. requried for normal sperm production and formation of characteristics associated with being a male

Down 2. gland that releases its products to the outside of the gland 3. gland that regulates calcium levels in bones and the blood 4. body system that includes glands and the hormones produced by them 6. disorder of the endocrine system in which pancreas fails to produce insulin (2 words) 7. master gland of the endocrine system; works directly with hypothalamus 9. glands that create gametes and sex hormones 11. hormone produced by adrenal glands that enhances the action of adrenaline 12. chemicals the "broadcast" message from the endocrine system 14. type of mechanism the endocrine uses to maintain homeostasis 15. gland that provides a place for T lymphocytes to mature 17. body system that controls and works closely with the endocrine system 18. organ that produces or releases a substance or secretion