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Antifungal & Antiviral Review

Dora Wiskirchen, PharmD, BCPS

A review of key concepts from the Day 2 AM Session lecture on antifungals and antivirals

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Across
7.brand name of posaconazole
9.prodrug of acyclovir
10.electrolyte affected by amphotericin B
13.Azole antifungals act on ________ synthesis
17.Toxicity associated with amphotericin B
18.an NSAID plus _____ are used as premeds for preventing infusion reactions with amphotericin B
22.antifungal that is a major substrate for 3A4
23.increased _____ is a side effect of valacyclovir
25.formulation component of IV voriconazole that accumaltes in renal impairment
27.Yeast that is NOT a Candida spp
28.CNS side effects are greater with this adamantane derivative
Down
1.Species of candida resistant to fluconazole
2.neuraminidase inhibitor associated with bronchospasm
3.Zygomycetes are classified as this type of fungi
4.side effect of tamilfu
5.brand name for liposomal amphotericin B
6.symptom of an infusion reaction associated with amphotericin B
8.This class of antifungals inhibit 1,3-b-d-glucan synthesis
11.Agent used in combination with amphotericin B for cryptococcus infections
12.Drug of choice for aspergillus
14.Dimorphic fungi often susceptible to fluconazole
15.azole antifungal with good oral bioavailability
16.foscarnet and ganciclovir are often used for treating _____ infections.
19.CNS side effect of voriconazole
20.side effect associated with acyclovir
21.Species of candida associated with parenteral nutrition
24.adamantane derivatives act on this in Influenza A
26.famciclovir inhibits _____ DNA synthesis

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