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Across 5. Fluid movement most notably of lymph fluid from circulation to tissue 9. Ab that have small AA difference but express no difference between binding 11. where the bacteria is digested 13. what has the shortest 1/2 life of in serum ______ 14. different biological activities, further classification of Ab along the isotypes 15. what is the structure of IgE 18. what kind of bond are held together in Ig. 19. what cause an decrease number of Fab binding Ag. 21. IgM have how many Fabs _______ 23. .Lots ___ for more flexibility. 24. complex of genes encoding cell surface that are required for antigen presentation to T cells 25. Light chain have 2 form_________ 26. IgM peak at how many days 27. cleaves disulfide bonds 29. antigen binding fragment 30. heavy chain and light chain have _____. 33. made by different alleles in individuals, found in constant regions of HC or LC. 34. enzyme catalyzing conversion for superoxide radical 35. products of chemical precipitation 36. what is most variable and has the most Ag contact.____ 37. secretes choleragon, binds to epithelial lining of gut, can cause dehydration. 39. What comprise hypervariable region. 41. Keratinocytes in epidermis produce 43. antigen presenting cell 44. Involved in polymerization of subunits of Ig. 45. intracellular vacuole containing ingested particulate material 47. includes disulfide bonds and lost of proline residues for flexiblity 49. what is the structure of IgA

Down 1. agent of precipitation 2. glycoprotein cytokines produced by certain cells that induce an antiviral state in other cells and also help to regulate immune response 3. what is the half life of IgM 4. This increase the chance of functional Ab being made. _______ 6. It is possible to have different AB causes with the smae: 7. Carbohydrates aid in associate with complement proteins for _. 8. Lots of _________ for disulfides. 10. a self molecule that attracts macrophages 12. what is the function of IgE. 16. what is the structure of IgM ______ 17. MALT tissue in small intestine 20. proteolytic cleavage used on IgG 22. fixed macrophage in the liver 28. Constant heavy chain domain is the example of _____ 31. which Ig has no protective function.____ 32. group of serum and cell membrane proteins that interact with one another and with other molecule of innate and adaptive immunity to carry out key effector functions. 38. cytokine that activates cytotoxic Tcell 40. Carbohydrates associated w/ ____. 41. secreted proteins that regulate the intensity and duration of the immune response by exerting a variety of effects on lymphocytes. 42. one of the products of a pepsin cleavage 46. only protein allowed in lymph fluid 48. Glycoprotein glycosylated in Golgi and ____