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DNA Synthesis

Storm E. Photon

Contains: DNA ligase, DNA polymerase, helicase, nucleotide excision repair, okazaki fragments, primase, replisome, RNA polymerase, semiconservative replication, SSBPs, telomerase, telomere, topoisomerase

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Across
1.Short segment of DNA produced during replication of the 5' to 3' template strand. Many of these make up the lagging strand in newly synthesized DNA.
4.One of a class of enzymes that catalyze synthesis of RNA from ribonucleotides using a DNA template.
5.An enzyme that synthesizes a short stretch of RNA to use as a primer during DNA replication.
10.An enzyme that cuts and rejoins DNA downstream of the replication fork, to ease the twisting that would otherwise occurs as the DNA "unzips".
11.An enzyme that catalyzes the breaking of hydrogen bonds between nucleotides of DNA, "unzipping" a double-stranded DNA molecule.
12.The region at the end of a linear chromosome.
13.The process of removing a damaged region in one strand of DNA and correctly replacing it using the undamaged strand as a template.
Down
2.The mechanism of DNA replication that results in each daughter DNA molecule containing one old and one new strand.
3.The multi-molecular machine that copies DNA; include DNA polymerase, helicase, primase, and other enzymes.
6.An enzyme that catalyzes synthesis of DNA from deoxyribonucleotides.
7.A class of proteins that attach to separated strands of DNA during replication or transcription, preventing them from re-forming a double helix. Also called single-stand DNA-binding proteins.
8.An enzyme that replicates the ends of chromosomes by catalyzing DNA synthesis from an RNA template that is part of the enzyme.
9.An enzyme that joins pieces of DNA by catalyzing formation of a phosphodiester bond between the pieces.

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