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Learn Pharmacology Through Puzzles (3)

Anwar Hamdi, M.D., Ph.D.

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3.This process limits the efficacy of many drugs when taken orally
6.A drug if given to neonates will result in gray baby syndrome
7.a drug that activates its receptor upon binding
9.the amount of drug in the body is reduced after administration but before entering the systemic circulation
11.a root of administration which has a 100% bioavailability
12.chemicals not normally produced or expected to be present in the body
14.a natural substances that inhibits drug metabolism by inhibiting CYP3A4
17.under the tongue
18.the actions of a drug on the body
19.working as a physiological antagonist for histamine
20.non-steroidal hormone that has intracellular receptors
21.reactions in metabolism that convert lipophilic molecules into more polar molecules by introducing or unmasking a polar functional group, such as –OH or –NH2
1.the maximal effect an agonist can produce
2.absorption of drugs which does not require energy, can be saturated, and may be inhibited by compounds that compete for the carrier
4.transporter protein responsible in the intestines for transporting drugs into the intestinal lumen and reducing drug absorption into the blood
5.a route of administration suitable if drug volume is moderate and suitable for oily vehicles and certain irritating substances
8.The driving force for absorption of a drug is the concentration gradient across a membrane separating two body compartments
10.a drug used in epilepsy and is capable of increasing the synthesis of one or more CYP isozymes
13.permits very large or very lipid-insoluble chemicals to enter cells
15.working as a chemical antagonist in the management of organophosphate cholinesterase poisoning
16.application of a drug to the skin for systemic effect

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