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Across 2. Kills only bacteria 4. mutagens that cause cancer in animals and humans 5. Protozoan parasite that causes African sleeping sickness 6. Removing all microbial life and destruction of all viable organisms 8. Type of mutation that inserts or deletes DNA 10. In replication, an enzyme that relaxes the supercoiling of DNA 12. Occurs from the 5'---to---3' direction in DNA 15. cancer of connective tissue 17. In this stage a capsid enters by receptor-mediated endocytosis or fusion 18. Recognition and binding site for RNA polymerase 19. Cyle where bacteriophages multiply and the host cell survives

Down 1. When genetic information transfers between cells of same generation 2. Viral DNA is replicated and some viral proteind are made 3. Another name for the spikes on the outside of the enveloped virus 7. DNA is integrated into a host cell chromosome 9. Major shape of a virus (called icosahedral) 11. An organisms genetic makeup, entire DNA 13. Strand where Okazaki fragments are made 14. Type of media that makes the plaque method possible 16. Extracellular state of a virus