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Across 5. Area of a burn injury surrounding the zone of coagulation that consists of cellular injury and compromised tissue perfusion. 6. Hyperpigmentation and accompanying erythema, induration, and plaque-like structural changes due to long-standing venous insufficiency. 8. Arterial insufficiency ulcer. 10. Indicator of surface blood flow. Normally less than 3 seconds. 11. Systemic, degenerative process in which the arterial lumen is gradually encroached upon by plaque formation. 12. Formula describing the determinants of the amount of compression exerted by a bandage. 13. Also called fourth-degree burn; results in destruction beyond the dermis down to fat, muscle, tendon, and/or bone. 14. Process of widening and deepening of a burn injury. 15. Surgical incision through fascia to release pressure and restore perfusion.

Down 1. Method of estimating burn size as a percent of total body surface area by dividing the body into sections roughly equal to 9% of totalbody surface area. 2. Occurs when the byproduct of the breakdown of red blood cells is forced into the interstitium by venous hypertension. 3. Theory that venous insufficiency ulcers are due to the development of fibrin cuffs around the capillaries. 4. Central portion of a burn injury that sustains irreparable damage. 7. Surgical incision through burn eschar to relieve pressure and restore perfusion. 9. Veins located within the subcutaneous tissues; assist with temperature regulation.