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Across 5. A mineral that is crucial for blood clotting 6. only vein to carry oxygenated blood (2 Words) 7. a chemical signal responsible for inflammation 8. blood vessels that are structurally reinforced to withstand the pressure of blood 14. puncture the foreign invader's cell membrane and destroy it (2 Words) 16. also known as white blood cells 17. divides the left and right chambers of the heart 19. A cell the engulfs foreign invaders in the body; non-specific defense 21. a molecule found on the surface of cells and pathogens; can be recognized by the immune system 22. supply the heard muscle with oxygen and nutrients (2 Words) 25. The fluid portion of blood 26. clumping together of incompatible blood types 30. a disorder where individuals bleed excessively; lack a clotting factor 31. Largest artery in the body 32. instrument used to listen to heart sounds 34. a cancerous overproduction of white blood cells 35. a factor in blood clotting 36. the pressure of blood pushing against the artery walls 37. proteins that recognize foreign substances in the body and neutralize or destroy them

Down 1. The universal acceptor blood type (2 Words) 2. smallest blood vessel that is 1 cell thick 3. The universal donor blood type (2 Words) 4. collects deoxygenated blood from the head and neck (3 Words) 9. read the antigen of an invader from a macrophage; identify the foreign invader (2 Words) 10. instrument used to measure blood pressure 11. the component of blood that binds oxygen 12. A valve on the left side of the heart (2 Words) 13. Collects deoxygenated blood from the lower extremeties (3 Words) 15. A valve on the right side of the heart (2 Words) 18. only artery to carry deoxygenated blood (2 Words) 20. mature in bone marrow; produce antibodies and retain as a blueprint against future attacks by foreign microbes 21. maintains osmotic balance 23. Also known as a red blood cell 24. blood vessels with 1-way valves leading towards the heart 27. the pressure of blood as the ventricles contract 28. the immune system of the body attacks itself 29. cells responsible for blood clotting after an injury 33. Known as the pacemaker (2 Words)