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Across 3. The site of the synapse between neuron one and neuron two of the autonomic nervous system. 4. A gland, organ, or tissue that responds to nerve stimulus with a specific action. 8. Activated by or transmitted through acetylcholine; also called parasympathomimetic. _________ drugs increase activity in the gastrointestinal tract. 10. A neurotransmitter that allows a nerve impulse to cross the synaptic junction (gap) between two nerve fibers or between a nerve fiber and an organ (e.g., muscle, gland). 12. An enzyme that brings about the breakdown of acetylcholine in the synaptic gap. 14. The absence of the sensation of pain. 16. A term used to describe an action or a receptor that is activated by epinephrine or norepinephrine. 17. That portion of the autonomic nervous system that arises from the thoracolumbar spinal cord, is mediated by catecholamines, and is concerned with the fight-or-flight response.

Down 1. That portion of the autonomic nervous system that arises from the craniosacral position of the spinal cord, is mediated by the neurotransmitter acetylcholine, and is concerned primarily with conserving and restoring a steady state in the body. 2. A state of involuntary muscle rigidity that is accompanied by immobility, amnesia, and variable amounts of analgesia. Some reflexes may be preserved. 5. Receptors activated by acetylcholine and nicotine found at the neuromuscular junction of the skeletal muscle and at the ganglionic synapse. 6. A drug that mimics the effects of stimulating the parasympathetic nervous system. 7. That portion of the nervous system that controls involuntary activities. 9. The class of neurotransmitters that includes dopamine, epinephrine, and norepinephrine. When given therapeutically, _________ mimic the effects of stimulating the sympathetic nervous system. 11. Receptors activated by acetylcholine and muscarine that are found in glands, the heart, and smooth muscle. An acronym for remembering _________ effects is SLUD (S-salivation, L-lacrimation, U-urination, D-defecation). 13. A drug that mimics the effects of stimulation the sympathetic nervous system. 15. The loss of all sensation. May be described as local (affecting a small area), regional, or surgical (accompanied by unconsciousness).