Across 1. The protein of a tumor suppressor gene; interprets growth signals and nutrient availability before allowing the cell cycle to proceed. 8. Division of the cytoplasm following mitosis or meiosis. 11. The stage of cellular reproduction in which nuclear division occurs; process in which a parent nucleus produces two daughter nuclei, each having the same number and kinds of chromosomes as the parent nucleus. 12. Ordered sequence of events in eukaryotes that involves cell growth and nuclear division that consists of stages. 13. When DNA synthesis or replication occurs. 14. A complex of microtubules and associated proteins that assist in separating the chromatids during cell division.

Down 2. The protein produced from a tumor suppressor gene that attempts to repair DNA damage or steps the cell cycle, or initiates apoptosis. 3. Cell grows in size, increases the number of organelles, and accumulate materials that will be used for DNA synthesis. 4. Stages of the cell cycle during which growth and DNA synthesis occur when the nucleus is not actively dividing. 5. Is the stage from the completion of DNA replication to the onset of mitosis. The cell synthesis proteins will assist cell division. 6. A hormone or chemical, secreted by one cell, that may stimulate or inhibit growth of another cell or cells. 7. Body cell; excludes cells that undergo meiosis and become sperm or eggs. 9. Programmed cell death; involves a cascade of specific cellular events leading to death and destruction of the cell. 10. Molecule that stimulates or inhibits an event in the cell.