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Across 3. 2nd most abundant extracellular anion 5. The part of a protein which acts as a weak base 7. Hormone which regulates water reabsorption in the kidney 9. Ion which acts as a weak base in the Phosphate buffer system 11. Ion which acts as a weak acid in the Carbonic acid - Bicarbonate buffer system 12. Most abundant mineral in the body 17. The part of a protein which acts as a weak acid 18. Ion with a negative charge 19. Fluid found in small spaces between cells 20. Hormone which stimulates sodium loss to decrease fluid in circultory system 22. A pH of 7 is considered _______ 25. The most abundant buffer in the body 26. Most abundant intracellular cation 27. Hormone which increases sodium reabsorption in the kidney 28. Most abundant extracellular anion

Down 1. Ion which acts as a weak base in the Phosphate buffer system 2. Ion with a positive charge 4. Compound with covalent bonds which does not dissociate in water 6. Measurement of the concentration of H+ and OH- ions 8. Most abundant extracellular cation 10. Water obtained through metabolism 13. Inorganic substance which splits into ions when placed in solution and can carry and electric current 14. Fluid outside of the cells 15. Ion which acts as a weak base in the Carbonic acid - Bicarbonate buffer system 16. Fluid within the cells 20. High concentration of H+ is considered _______ 21. Water ingested with food or drink 23. High concentration of OH- is considered _______ 24. A chemical which presents a drastic change in pH of a fluid