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Across 2. What development stage does translation gene regulation occur 4. Ribonucleases are secreted out of which organ 6. Location of RNA processing 7. Prokaryotic genes are mainly regulated by 9. PRPP inhibited by 13. A drug that inhibits the initiation of transcription 14. Process formRNA to Protein 16. Zinc-fingers contain 2 cysteines and 2--- residues 17. What type of linkage bonds the ribose sugar and nucleotide 19. Prokaryotic genes are organized into 21. Which form of DNA seen under physiological conditions 23. Conserved from early stages of evolution 24. The site of protein synthesis 25. High levels of uric acid in blood 26. Type of intramolecular bonds that hold DNA base pairs together 27. Process in RNA synthesis cause the local unwinding of DNA helix 28. A specialized transcriptional factor binds the domain of the nucleus 30. Signal pathway primarily utilized by Nuclear receptor signaling 32. A testicular cancer drug that convalently attatches to G residue in DNA 36. Translation machinery 38. Enzyme that Hydrolyzes phosphate groups during Nucleotide degradation 40. Carries information for more than one gene 41. Amino acids are held together by which type of bond 42. Responsible for the local DNA unwinding 46. Inactive gene segments found in 49. Source of amine group in the synthesis of GMP 50. Carries info for one gene 51. Nucleic acid and ribose sugar without phosphate group 52. Actively transcribed genes found in 53. Type of DNA that links nucleosomes 54. In nucleosomes what does eukaryotic DNA bind to 55. Used to treat chronic myelogenous leukemia and sickle cell disease 56. Suicide inhibitor for Thmidylate Synthase 57. A particular codon always codes for an amino acid

Down 1. DNA sequences associated with increase in transcription factors 2. Where are Ribosomal proteins mainly found 3. A given amino acid that has more than on e codon 5. Product of AMP synthesis 8. how is ρ-independent terminated 10. How are cysteine and histidine residues linked in Zinc loops 11. Catalyzes formation of peptide bonds that link amino acid residues 12. Location of CPS II 13. type of reaction nucleoside phosphate reductase undergo 15. Primary C donor in pyrimidine ring 18. Z-DNA binding proteins are required for viral 20. What are recognized by basal transcriptional factors 22. Uric acid is excreted 29. Adenosine deaminase deficiency is an accumulation of 30. One carbon donor 31. 3 codon sequence on tRNA that binds mRNA 33. Which specialized transcriptional factor dimerizes by means of amino acid zipper 34. Codes is read from a fixed starting point as a continuous 35. Nucleotide structure not in RNA 37. What is the sequence for early degradation 39. The protein classification of Zinc finger transcriptional factors 43. Major mechanism of gene regulation in eukaryotes and prokaryotes 44. Interferes with synthesis of nucleotides 45. Cannot be varied on mRNA 47. Type of DNA that is stored in chromosomes as superhelix 48. Carries information from DNA to protein