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Across 3. Division of the cytoplasm to form two separate daughter cells. 6. The fourth and final phase of mitosis where the chromosomes, which were distinct and condensed begin to spread out into a tangle of chromatin. 7. Region of a chromosome where the two sister chromatids attach. 10. Type of reproduction in which cells from two parents unite to form the first cell of a new organism. 11. The period in interphase when the cell is growing and just “doing its job.” 12. Apparatus composed of microtubules that orchestrates the movement of chromosomes during mitosis. 15. Cell organelle that houses the cell’s DNA and directs ribosome and protein synthesis. 19. A disorder in which some of the body’s cells lose the ability to control growth. 20. Mechanism that may stop the progress of a cell as it moves through the cell-cycle stages. 21. A series of events in which a cell grows, prepares for division, and divides to form two daughter cells. 22. Spindle fibers extend from this tiny pair of structures to the centromeres. Only seen in animal cells. 23. The second phase of mitosis where the centromeres of the duplicated chromosomes line up across the “equator” of the cell. 24. Single DNA molecule of two strands of duplicated DNA and associated proteins held together at the centromere.

Down 1. The period in interphase when the DNA is duplicated. 2. The third phase of mitosis where the chromosomes separate and move along the spindle fibers to opposite ends of the cell. 4. The production of genetically identical offspring from a single parent cell. 5. The period in interphase after DNA duplication, when the cell is growing and duplicating all the other organelles in preparation for mitosis. 8. The first phase of mitosis where the genetic material inside the nucleus condenses and the duplicated chromosomes become visible. 9. Process of prokaryotic cell division. 13. Part of eukaryotic cell division during which the cell nucleus divides; the cell spends about 10% of its time in this phase. 14. The cell spends about 90% of its time in this phase, growing, and duplicating DNA in preparation for the mitotic phase. 16. One of two identical “sister” parts of a duplicated chromosome. 17. The cytoskeleton system's largest element; pulls replicated chromosomes to opposite ends of a dividing cell. 18. Unspecified cell that can give rise to one or more types of specialized cells. 19. Structure formed during plant cell cytokinesis by Golgi vesicles, forming a temporary structure (phragmoplast) at the metaphase plate; ultimately leading to a new cell wall. 20. Genetic information that is bundled into packages of DNA.