| Erasmus | | Selected Florence's Council of Seventy |
| Niccolo Machiavelli | | Discovered and destroyed the Aztecs for gold |
| Leonardo da Vinci | | Started the first trip that went all the way around the world |
| Michelangelo | | Discovered and destroyed the Incas for gold |
| Fra Angelico | | Discovered America |
| Ferdinand and Isabella of Spain | | 'Praying Hands' |
| Donatello | | Named America |
| Rafael | | 'Mona Lisa' |
| Brunellsechi | | 'The Ship of Fools' |
| Cosimo de Medici | | 'The Dome of Florence' |
| Ivan the Great | | Paintings of Dante's Divine Comedy |
| Lorenzo the Magnficent | | Painted 'School of Athens' |
| Sandro Botticelli | | the first Platonic Academy in 1445 |
| Christopher Columbus AKA Cristóbal Colón | | the Spanish Inquisition |
| Amerigo Vespucci | | 'In Praise of Folly' |
| Savonarola | | 'The Arnolfini Marriage' |
| Jan van Eyck | | 'The Prince' |
| Jerome Bosch | | 'Equestrian Statue of Gattamelata' |
| Albrecht Dürer | | Ceiling of the Sistine Chapel |
| Pieter Bruegel | | "The Lord has suffered much for me." |
| Martin Luther | | Shook Russia free from the Mongols and rebuilt the Kremlin |
| Hernán Cortés | | 'Ninety-five Theses' |
| Francisco Pizarro | | 'The Tower of Babel' |
| Ferdinand Magellan | | 'The Annunciation' |