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Across 3. Killed 60% of the population of some cities 8. The farthest spot on the horizion in a painting 11. Most Italians were members of this church 12. Wrote about how to be an effective ruler 13. She was the patron who defended Mantua and built a famous art collection 15. Son of Cosimo de' Medici 17. Why northern Europe laged behind the rest of the world 20. Church designed by Michelangelo 22. Fresco of Christ and the apostles 25. Wealthiest, most powerful class of people 28. Boccaccio's book about times during the plague 29. Language of the common people 31. Humanist who wrote sonnets 32. City the Medici family ruled 33. City of the headquarters of the Catholic Church 34. Financial supporter of the arts 35. These wars spurred overseas trade

Down 1. City poplation centers 2. Indicates three dimensions in a painting 4. The wealthiest European of his time 5. Made sculpture more realistic by carving natural postures and expressions 6. Famous female painter Sofonisba ________ 7. They took Constantinople in 1443 9. Took four years to paint the ceiling here 10. Carved "David", painted the Sistine chapel, and designed St. Peter's 14. Book that describes the "Renaissance Man" 16. Focused on human potential and achievements 18. Renaissance means _____ 19. Years from 1300-1600 21. Painted the "School of Athens" 23. Book about how to be politically effective 24. Painter of the "Mona Lisa" 26. Worldly, concerned with the here and now 27. The first European large free-standing nude since ancient times 30. Farm areas